G418 Disulfate (syn: Geneticin) is an aminoglycoside antibiotic isolated from Micromonospora rhodorangea and is similar in structure to Gentamicin B1. G418 is an analog of Neomycin Sulfate and has a similar mechanism to Neomycin. It has a broad range of in vitro and in vivo antibacterial activity. It is routinely used for gene selection in cell culture, for selection and maintenance of both prokaryotic and eukaryotic cells transfected with neomycin resistance gene.
G418 Disulfate is soluble in water.