5-Fluorouracil F034-5G

产品介绍

5-Fluorouracil is a synthetic growth inhibitor and a thymidylate synthase (TS) inhibitor.  It is named as there is a fluorine atom on the 5th carbon of a uracil ring.  Fluorouracil was patented in 1956 (Hoffman La-Roche).  Metabolites of 5-Fluorouracil use multiple targets to slow DNA and RNA processing and therefore cell growth. The compound can inhibit human cell growth, induce apoptosis and can be used as an anti-cancer agent.  Derivatives of 5-Fluorouracil were isolated from the marine sponge Phakellia fusca, which is unusual since anti-cancer agents usually do not have analogs in nature.

5-Fluorouracil is sparingly soluble in water and slightly soluble in alcohol.

This product is considered a dangerous good. Quantities above 1 g may be subject to additional shipping fees. Please contact us for questions.