Cefaclor is a second generation cephalosporin antibiotic derived from the Acremonium fungus. Cefaclor is slightly soluble in aqueous solution (8.6mg/mL).
CAS Number: 53994-73-3
Molecular Formula: C15H14ClN3O4S • H2O
Molecular Weight: 385.82
Mechanism of Action: Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases.
Storage Conditions: -20°C
Tariff Code: 2941.90.3000