Bacitracin CulturePure® B014-10G

产品介绍

Bacitracin is a branched cyclic dodecylpeptide antibiotic produced by Bacillus licheniformis and some strains of Bacillus subtilis (Azevedo et al 1993).  It is synthesized as a mixture of up to 50 closely related congeners/fractions.  Bacitracin includes the following fractions: A, A1, B, B1, B2, B3, C, C1, C2, C3, D, E, F, G, H1, H2, H3, I1, I2, I3, and X.  Bioactive components include  A, B1, B2, and B3. Bacitracin is freely soluble in aqueous solution.

During the purification of Bacitracin, many peptide precursors are not removed and are detectable in finished commercial products. These peptides have an affinity for cell walls much like bioactive Bacitracin components.  Liquid column chromatography is used to separate the impurities from the bioactive components.  Each component has been collected and carefully tested for toxicity against routinely used cell lines. Only bioactive, non-toxic fractions are included in Bacitracin, CulturePure.

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