Lipid peroxidation may impact biological membranes by altering structure, permeability and function, and is implicated in a number of disease states. Metabolic breakdown of the altered lipids results in the formation of “secondary messengers” including malondialdehyde (MDA), 4-hydroxynonenal and others. Measurement of MDA allows an assessment of oxidative stress. The TBARS Malondialdehyde Oxidative Stress Assay relies upon the reaction of thiobarbituric acid and MDA under acidic conditions to form a colored (and fluorescent) adduct. Our kit is designed to allow ready assessment of TBARS MDA equivalents in biological samples using fluorometric or spectrophotometric methods.
Specimen: Universal
# Plates: 1 x 96 well plate