Tensin 4 VHH Antibody ; Z-N010 10UG

产品介绍

Recombinant anti-Tensin 4 Nanobody, Clone # Nb12, COOH-terminal HA tag. Type: VHH single domain Source: E. Coli Applications: ELISA, Immunoprecipitation, Pull down Clonality: Monoclonal Background: Tensin 4 VHH Antibody was produced in an llama with a fragment of Tensin4 encompassing residues 428-714 then cloned for recombinant production in E. Coli. Tensin, aka TNS4 or CTEN, is a component of the cytoskeleton and localizes close to or at focal adhesions, connecting the cytoplasmic tail of integrins with actin filaments. It contains a C-terminal SH2 and PTB (phosphotyrosine binding domain) and binds tyrosine-phosphorylated proteins that assemble into signaling complexes at focal adhesions. Its expression has been reported to be down regulated in prostate cancer, but upregulated in lung and breast cancer. Recombinant anti-Tensin 4 Nanobody 12 was developed by Gulliver Biomed.