Recombinant anti-p53 Nanobody, Clone # Nb139, COOH-terminal HA tag. Type: VHH single domain Source: E. Coli Applications: ELISA, Immunoprecipitation, Pull down Clonality: Monoclonal Background: p53 DBD VHH Antibody was produced in an alpaca with human recombinant p53 DNA-binding domain then cloned for recombinant production in E. Coli. p53 is a tetrameric transcription factor and tumor suppressor that controls numerous aspects of cellular behavior. Mutations in p53 are observed in over 50% of human cancers with several hot spot mutations occurring in the DNA binding domain of p53. Recombinant anti-p53 Nanobody 139 was developed by Gulliver Biomed. |