Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1,4-bisphosphate (Ins(1,4)P2) is an intermediate in the inositol phosphate pathway. It is produced by dephosphorylation of Ins(1,4,5)P3 by a 5-phosphatase thus terminating IP3 signaling. Ins(1,4)P2 is also a substrate for inositol 1-phosphatase. |