PtdIns(3,4,5)P3 3-phosphothioate, diC16 (3S-PtdIns(3,4,5)P3, diC16) is a synthetic PI(3,4,5)P3 analog in which the 3-phosphate has been rendered metabolically stable as a phosphorothioate. P-3S916 increases sodium transport across monolayers of cells A6 through activation of GLUT4. |