PI(3, 4)P2 diC8 ; P-3408 1MG

产品介绍

PI(3,4)P2 diC8 (Phosphatidylinositol 3,4-bisphosphate diC8) is a synthetic, purified dioctanoyl PI(3,4)P2. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP, TPTE, etc.). PI(3,4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions. Product Keywords: Dioctanoyl Phosphatidylinositol 3,4-bisphosphate, PtdIns(3,4)P2 C8, PI(3,4)P2 C8, or PI34P2. Bulk discounts available, please email echelon@echelon-inc.com for details.