PI(3)P diC8 (Phosphatidylinositol 3-phosphate diC8) ammonium salt is a synthetic, purified dioctanoyl PI(3)P. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4. |