1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphoinositol (16:0 LysoPI, LPI) is a synthetic, purified palmitoyl PI. Lysophospholipids are lipid mediators which elicit a diverse array of cellular responses through activation of phospholipid specific G protein-coupled receptors. Lysophosphatidylinositol (LPI) induces a number of cellular effects through binding to the GPR55 receptor including angiogenesis, bone morphogenesis, cancer progression and pain. In addition LPI is thought to be a biomarker for certain cancers. |