Glycerophosphoinositol (GroPI) is the building block for phosphoinositide polyphosphates and is a substrate for PI-PLC. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol. Bulk discounts available, please email echelon@echelon-inc.com for information. |