ALC-0159 is a PEGylated lipid which has been used to form lipid nanoparticles for delivery of RNA. ALC-0159 is one of the components in the BNT162b2 vaccine against SARS-CoV-2 in addition to ALC-0315, DSPC, and cholesterol. A small amount of a PEG derivatized lipid like ALC-0159 [0.5-3%] is incorporated into LNPs to increase the circulatory half-life in the body. This is a reagent grade product, for research use only. |