产品介绍
| Purity >95%, by SDS-PAGE under reducing conditions and visualized by silver stain Endotoxin Level <0.01 EU per 1 μg of the protein by the LAL method. Activity Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340. The ED50 for this effect is 5-30 ng/mL in the presence of 3 ng/mL of recombinant human Activin A. Source Mouse myeloma cell line, NS0-derived mouse Activin RIIB protein Mouse Activin RIIB (Ser19-Thr134) Accession # P27040 IEGRMDP Mouse IgG2A (Glu98-Lys330) N-terminus C-terminus Accession # P27040 N-terminal Sequence Analysis Ser19 Structure / Form Disulfide-linked homodimer Predicted Molecular Mass 40.5 kDa (monomer) SDS-PAGE 61-63 kDa, reducing conditions |