产品介绍
| Purity >95%, by SDS-PAGE under reducing conditions and visualized by silver stain Endotoxin Level <0.01 EU per 1 μg of the protein by the LAL method. Activity Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340. Approximately 0.3-1 µg/mL of rhActivin RIIB/Fc Chimera will inhibit 50% of the biological response due to 3 ng/mL of rhActivin A. Source Mouse myeloma cell line, NS0-derived human Activin RIIB protein Met Human Activin RIIB (Ser19 - Thr 134) Accession # CAA54671 IEGRMD Human IgG1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus Accession # CAA54671 N-terminal Sequence Analysis Met Structure / Form Disulfide-linked homodimer Predicted Molecular Mass 41 kDa (monomer) SDS-PAGE 60 kDa, reducing conditions |