产品介绍
| Purity >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. Endotoxin Level <1.0 EU per 1 μg of the protein by the LAL method. Activity Measured by its ability to inhibit the biological activity of Neuregulin-1-beta 1 on MCF‑7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083. The ED50 for this effect is 0.3-3 µg/mL in the presence of 10 ng/mL Recombinant Human NRG1‑ beta 1/HRG1‑ beta 1 Extracellular Domain (Catalog # 377-HB). Source Human embryonic kidney cell, HEK293-derived human ErbB3/Her3 protein Human ErbB3/Her3 (Ser20-Gly538) Accession # P21860-1 YSKGSQSRMGGGGALQWNCSGGIQ 6-His tag N-terminus C-terminus Accession # P21860.1 N-terminal Sequence Analysis Ser20 Predicted Molecular Mass 61 kDa SDS-PAGE 73-83 kDa, under reducing conditions |