Zaragozic acid A Z006-1MG

产品介绍

Zaragozic Acid A is the major metabolite of a class of unusual bicyclic tricarboxylic acids, produced by a number of fungi in the genera Curvularia, Exserohilum, Setosphaeria and others, discovered at Merck and Glaxo in the early 1990s. Zaragozic Acid A is presented as the free acid rather than the tri-sodium salt to avoid stability problems associated with hydrolysis of the salt.

Zaragozic acids are natural products, the first ones being characterized were Zaragozic Acid A, B and C from fungal cultures of an unidentified culture, Sporormiella intermedia, and Leptodontium elatius respectively.  

The Zaragozic acids are characterized by a novel 2,8-dioxobicyclo[3.2.1]octane-4,6,7- trihydroxyl-3,4,5-tricarboxylic acid core and differ from each other in the structures of the 6-acyl and 1-alkyl side chains.


Zaragozic Acid A is soluble in ethanol, methanol, DMF and DMSO.  It has moderate water solubility.