Temsirolimus T077-5MG

产品介绍

Temsirolimus is a semisynthetic macrocyclic lactone prepared from Rapamycin.  It is a dihydroxymethyl propionic acid ester and analog of Rapamycin. The compound is prepared by selective acylation of the 42-hydroxy group with a protected bis (dihydromethyl) propionic acid, followed by deprotection.

Temsirolimus is an antiproliferative and antiangiogenic mTOR inhibitor.  mTOR protein has a role in integrating environmental signals that affect cell growth and proliferation.  It has anti-neoplastic properties and immune-modulating activity. It can be used in kinase phosphatase biology research.

Temsirolimus is soluble in ethanol, methanol, DMF and DMSO.