Pyripyropene A is a meroterpenoid isolated from Aspergillus fumigatus and published in 1993 by Omura and co-workers at the Kitasato Institute, Japan. Pyripyropene A has potent acyl-CoA:cholesterol acyltransferase (ACAT) and the isozyme sterol Oacyltransferase 2 (SOAT2) inhibitory activity, thus inhibiting the conversion of cholesterol to cholesteryl esters. Pyripyropene A is active against aphids in field trials and has weak insect anti-feedant activity.