产品介绍
Puromycin is an aminonucleoside antibiotic with anti-trypanosomal and antineoplastic properties. It was isolated from Streptomyces alboniger in the 1950s. Puromycin is used in cell biology to select for mammalian cell lines that have been transformed with the pac gene and express puromycin-N-acetyl-transferase. Puromycin is a reversible inhibitor of dipeptidyl-peptidase II (serine peptidase) and cytosol alanyl aminopeptidase (metallopeptidase). Puromycin has anti-cancer properties, inducing apoptosis in breast cancer cells. Puromycin is soluble in water, ethanol, methanol, DMSO and DMF.