Polymyxin E2 Sulfate, EvoPure® (syn: Colistin B) is one of the two major components of Polymyxin E (Colistin). Polymyxin E1 and E2 are structurally similar and differ only by a fatty acid group at the N-terminus. Polymyxin E1 contains 6-methyloctanoic acid and Polymyxin E2 (Colistin B) contains 6-methylheptanoic acid. Together, Polymyxin E1 and E2 comprise approximately 85% of Polymyxin E; however, 13 different Polymyxin E components have been indentified.