Polymyxin B1-I Sulfate, EvoPure® (syn: Isoleucine (Ile)-B1) is one of the individual polypeptide components in Polymyxin B Sulfate. Polymyxin B1-I contains, among other amino acids, an L-isoleucine residue in place of the L-leucine reside found in the other polymyxin fractions. The unique fatty acid group found in B1-I is 6-methyloctanoic acid (6-MOA), the same group found in Polymyxin B1. Results from in vitro studies have shown marginal differences in MIC data when comparing the fractions.