Kazusamycin B K019-0.5MG

产品介绍

Kazusamycin B is a metabolite and minor member of the Leptomycin complex isolated from some Streptomyces species. It is a hydroxylated analog of Leptomycin A, a nuclear export inhibitor. It is similar to Leptomycins A and B in physico-chemical and biological characteristics. It has anti-cancer properties.  This metabolite can inhibit nuclear export and translocation of Rev, a gene product in the HIV-1 genome, at nanomolar concentrations.

Kazusamycin B is soluble in ethanol and methanol but is practically insoluble in water.  It is unstable in DMSO.