Kazusamycin A K018-0.1MG

产品介绍

Kazusamycin A is a minor member of the Leptomycin complex isolated from some Streptomyces species. It is a hydroxylated analog of Leptomycin B, a nuclear export inhibitor. It is similar to Leptomycins A and B in physico-chemical and biological characteristics. It has anti-cancer properties.  It can inhibit nuclear export and Rev translocation, a gene product in HIV-1 genome, at nanomolar concentrations.

Kazusamycin A is soluble in ethanol, methanol, ethyl acetate, acetone, chloroform and benzene, practically insoluble in water, and unstable in DMSO.