Kendomycin is an unusual macrocyclic metabolite containing a rare quinone methide group. Kendomycin is a potent antibacterial agent against Gram positive and Gram negative bacteria, including MRSA strains, also displaying antitumor activity. Kendomycin is a potent endothelin receptor agonist and demonstrates antiosteoporotic activity.
Kendomycin is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.