Ivermectin monosaccharide is a semi-synthetic produced by selective hydrolysis of the terminal saccharide unit of ivermectin. Ivermectin monosaccharide is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The monosaccharide is used as a sensitive probe for the detection of some types of ivermectin resistance.
Ivermectin monosaccharide is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.