Derquantel D046-5MG

产品介绍

Derquantel is a semi-synthetic paraherquamide analog, derived from a fermentation product of Penicillium simplicissimum via chemical reduction.  It is an anthelmintic spiroindole that acts as a nicotinic acetylcholine receptor antagonist.  Derquantel is a potent nematocide and was the first paraherquamide to be successfully commercialised in combination with avermectin.  The compound is prepared by removal of the 2-oxo group in a four-step sequence of N-protection, reduction, N-deprotection and a final reduction.