Deoxyfusapyrone is a broad spectrum antifungal metabolite isolated from several Fusarium species, first reported in 1994. Deoxyfusapyrone exhibits low zoo-toxicity as evidenced by a lack of toxicity against Artemia salina and is a useful candidate for control of postharvest crop diseases. Like the related fusapyrone, its mechanism of action is unknown and its structure was revised in 2006.