Actagardin is a high molecular weight tetracyclic antibiotic produced by several species of Actinoplanes. Actagardin is an antibiotic in which the macrocyclic rings are formed by thioether, rather than disulphide, bridges. Actagardin is a potent Gram positive and Gram negative antibiotic. Actagardin acts by inhibition of peptidoglycan biosynthesis.
Actagardin is soluble in ethanol, methanol, DMF and DMSO.