Albumin Depletion From Serum or Plasma
Removes 30 mg albumin/ml, >90%
Affinity-type equivalence, virtually no cross-reactivity with other proteins
Disposable, no column regeneration or cross-contamination
Economical new surface technology, not based on blue-dye or immuno-affinity chromatography
Mild binding conditions maintains tertiary structure and simple transfer to secondary analysis
The flow-through (unbound) fractions retain their enzymatic and biological activity
Removes albumin from most species including human, sheep, bovine, mouse, goat, rat, and calf.
Validated in the automation compatible high-throughput DPX Technologies XTR tip format
Poly-electrolytes are polymers with repeating units of stationary charges. AlbuSorb™ comes from a class of solid-phase, or bead-based, elastomeric poly-electrolytic beads that bind proteins through an empirically derived chemistry combining elements of polymer composition, cross-linking architecture and charge properties. As with bio-polymers like DNA and Heparin, governing their reactivity is the spatial presentation of the electrostatic groups along a flexible polymer chain.
Unlike immuno-affinity, the surfaces utilized are disposable eliminating cycle to cycle variance and cross-contamination. AlbuSorb™ is supplied as a dry powder. Simply weigh, centrifuge and/or filter, and recover the albumin depleted serum in the supernatant.