Tedizolid Phosphate T118-10MG

产品介绍

Tedizolid Phosphate is a second-generation oxazolidone antibiotic.  It is a phosphate ester precursor to Tedizolid, the active compound.  It is bacteriostatic against Gram-positive organisms.

Tedizolid Phosphate was developed by Cubist Pharmaceuticals, following acquistion of Trius Pherapeutics.  It differs from other oxazolidinones by having a modified side chain at the C-5 position of the oxazolidinone nucleus which confers activity against certain linezolid-resistant pathogens.  It also has an optimized C- and D-ring system that improves its potency via addiitonal binding site interactions.  The compound was formerly known as Torezolid.  Tedizolid is bacteriostatic against Gram-positive organisms.  As with linezolid, Tedizolid is a weak, reversible MAO inhibitor.

Tedizolid Phosphate is slighty soluble in DMSO, but insoluble in water and ethanol.