产品介绍
| Name Phosphodiesterase 1C (PDE1C) ACTOne™ Stable Cell Line Description This cell line is a HEK293-CNG-sGC cell line that expresses a recombinant human PDE1C. HEK293-CNG-Gs cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Application cAMP dependent human PDE1C cell-based assay; Cell-based high-throughput screening of human PDE1C agonists/antagonists. Size 1x 106 cells Detection FlexStation or Microplate reader |