CL-03-PDE1B ; Phosphodiesterase 1B (PDE1B) Stable Cell Line (HEK293)

产品介绍

Name Phosphodiesterase 1B (PDE1B) ACTOne™ Stable Cell Line Description This cell line is a HEK293-CNG-Gs cell line that expresses a recombinant human PDE1B. HEK293-CNG-Gs cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently results in ion flux and cell membrane depolarization. Application cAMP dependent human PDE1B cell-based assay; Cell-based high-throughput screening of human PDE1B agonists/antagonists Size 1x 106 cells Detection FlexStation or Microplate reader