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CL-03-PDE10A ; Phosphodiesterase 10A (PDE10A) Stable Cell Line (HEK293)

  • 价格:¥7,000.00 元

产品介绍

    Name

    Phosphodiesterase 10A (PDE10A) ACTOne™ Stable Cell Line

    Description

    This cell line is a HEK293-CNG-Gs cell line that expresses a recombinant human PDE10A. HEK293-CNG-Gs cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently results in ion flux and cell membrane depolarization. 

    Application

    cAMP dependent human PDE10A cell-based assay;

    Cell-based high-throughput screening of human PDE10A agonists/antagonists.

    Size

    1x 106 cells

    Detection

    FlexStation or Microplate reader


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