CL-03-PDE10A ; Phosphodiesterase 10A (PDE10A) Stable Cell Line (HEK293)

产品介绍

Name Phosphodiesterase 10A (PDE10A) ACTOne™ Stable Cell Line Description This cell line is a HEK293-CNG-Gs cell line that expresses a recombinant human PDE10A. HEK293-CNG-Gs cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently results in ion flux and cell membrane depolarization.  Application cAMP dependent human PDE10A cell-based assay; Cell-based high-throughput screening of human PDE10A agonists/antagonists. Size 1x 106 cells Detection FlexStation or Microplate reader