Name Phosphodiesterase 4D (PDE4D) ACTOne™ Stable Cell Line Description This cell line is a CHO-K1-CNG cell line that expresses a recombinant human PDE4D. CHO-K1-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently results in ion flux and cell membrane depolarization. Application cAMP dependent human PDE4D cell-based assay; Cell-based high-throughput screening of human PDE4D agonists/antagonists. Size 1x 106 cells Detection FlexStation or Microplate reader |