Name Phosphodiesterase 4C (PDE4C) ACTOne™ Stable Cell Line Description This cell line is a CHO-K1-CNG cell line that expresses a recombinant human PDE4C. CHO-K1-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently results in ion flux and cell membrane depolarization. Application cAMP dependent human PDE4C cell-based assay; Cell-based high-throughput screening of human PDE4C agonists/antagonists Size 1x 106 cells Detection FlexStation or Microplate reader |