产品介绍
| Name Thyroid Stimulating Hormone Receptor (TSHR) ACTOneTM Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human TSHR. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader. Application cAMP dependent human TSHR cell-based assay; cell-based high-throughput screening of human TSHR agonists/antagonists Size 1x 106 cells Detection FlexStation or Microplate reader |