Name Sphingosine-1-Phosphate Receptor 3 (S1PR3) ACTOneTM Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human S1PR3. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Application cAMP dependent human S1PR3 cell-based assay; Cell-based high-throughput screening of human S1PR3 agonist/antagonist. Size 1x 106 cells Detection FlexStation or Microplate reader |