产品介绍
| Name Parathyroid Hormone 1 Receptor (PTH1R) ACTOneTM Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human PTH1R. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader. Application cAMP dependent human PTH1R cell-based assay; Cell-based high-throughput screening of human PTH1R agonists/antagonists. Size 1x 106 cells Detection FlexStation or Microplate reader |