Name Adenylate Cyclase Activating Polypeptide 1 Receptor (PAC1R, ADCYAP1R1) ACTOneTM Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human PAC1R. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Application cAMP dependent human PAC1R cell-based assay; Cell-based high-throughput screening of human PAC1R agonists/antagonists. Size 1x 106 cells Detection FlexStation or Microplate reader |