CL-11-OPRM1 ; Opioid Receptor, Mu 1 (OPRM1) Stable Cell Line

产品介绍

Name Opioid Receptor Mu1 (OPRM1) ACTOneTM Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human OPRM1. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FDSS, FLIPR, or a fluorescence microplate reader. Application cAMP dependent assay for Gi-coupled human OPRM1; Cell-based high-throughput screening of human OPRM1 agonists/antagonists. Size 1x 106 cells Detection FlexStation or Microplate reader