产品介绍
| Name Opioid Receptor Kappa 1 (OPRK1) ACTOneTM Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human OPRK1. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FDSS, FLIPR, or a fluorescence microplate reader. Application cAMP dependent assay for Gi-coupled human OPRK1; Cell-based high-throughput screening of human OPRK1 agonists/antagonists. Size 1x 106 cells Detection FlexStation or Microplate reader |