CL-11-NPY1R ; Neuropeptide Y Receptor Y1 (NPY1R) Stable Cell Line

产品介绍

Name Neuropeptide Y Receptor Y1 (NPY1R) ACTOneTM Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human NPY1R. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader Application cAMP dependent assay for Gi-coupled human NPY1R Cell-based high-throughput screening of human NPY1R agonists/antagonists. Size 1x 106 cells Detection FlexStation or Microplate reader