CL-01-MC5R ; Melanocortin 5 Receptor (MC5R) Stable Cell Line

产品介绍

Name Melanocortin 5 Receptor (MC5R) ACTOneTM Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human MC5R. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader. Application cAMP dependent human MC5R cell-based assay; Cell-based high-throughput screening of human MC5R agonists/antagonists. Size 1x 106 cells Detection FlexStation or Microplate reader