产品介绍
| Name Melanocortin 4 Receptor (MC4R) ACTOneTM Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human MC4R. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.< Application cAMP dependent human MC4R cell-based assay; cell-based high-throughput screening of human MC4R agonists/antagonists. Size 1x 106 cells Detection FlexStation or Microplate reader |