CL-01-HTR7B ; 5-Hydroxytryptamine (Serotonin) Receptor 7B (HTR7B) Stable Cell Line

产品介绍

Name 5-Hydroxytryptamine (Serotonin) Receptor 7B (HTR7B) ACTOneTM Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human HTR7B. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader. Application cAMP dependent human HTR7B cell-based assay; cell-based high-throughput screening of human HTR7B agonists/antagonists. Size 1 mL (frozen cells, 1x 106 cells before freezing) Detection FlexStation or Microplate reader