Name 5-Hydroxytryptamine (Serotonin) Receptor 1A (HTR1A) ACTOneTM Stable Cell Line Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human HTR1A. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Application cAMP dependent human HTR1A cell-based assay; Cell-based high-throughput screening of human HTR1A agonists/antagonists. Size 1 mL (frozen cells, 1x 106 cells before freezing) Detection FlexStation or Microplate reader |