产品介绍
| Name Metabotropic Glutamate Receptor 4 (GRM4) ACTOne>TM Stable Cell Line Description This cell line is a HEK-293 CNG-Slcla3 cell line that expresses a recombinant human GRM4. HEK-293 CNG-Slcla3 cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader. Application cAMP dependent human GRM4 cell-based assay; cell-based high-throughput screening of human GRM4 agonists/antagonists. Size 1x 106 cells Detection FlexStation or Microplate reader |