产品介绍
| Name Calcitonin Receptor-like Receptor (CRLR) ACTOneTM Stable Cells Description This cell line is a HEK-293-CNG cell line that expresses a recombinant human CRLR. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader. Application cAMP dependent human CRLR cell-based assay; Cell-based high-throughput screening of human CRLR agonists/antagonists. Size 1x 106 cells Detection FlexStation or microplate reader |